Chirale oxazolidinones are structural building blocks for innovative active agents
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This systematic work is the precondition to manage the use of oxidases for a multiplicity of environment-friendly production processes of important fine chemicals in a technical scale.
The processed oxidases are about a D-amino acid oxidase from the bacterium Arthrobacter, the L-amino acid oxidase from a Rhodococcus strain as well as the NADH-oxidase from a Lactobacillus brevis. These oxidases were produced, biochemically characterised and two of them even crystallised. Exemplary oxidase-catalysed applications were performed in a small scale and then received an online tracking with help of a specifically developed instrument, the RAMOS-technology.
Projektziel:
New bacterial oxidases
Projektträger:
AC Biotec GmbH
Dr. Tibor Anderlei
Prof.-Rehm-Straße 1
52428 Jülich
Telefon:
+49-2461-980119
Fax:
+49-2461-980450
URL:
www.acbiotec.com
E-Mail:
r.anderlei@acbiotec.com