The platform chemical 7-ACA serves as a starting material, which is already today accessible by means of a sustainable approach. Among the semisynthetic cephalosporin drugs a particular focus of this project is on the industrially important products being produced on tons scale such as cefotaxime or ceftriaxone.

Desired features being envisaged for all syntheses are excellent space-time-yields, substrate concentrations and yields as well as technical feasibility. A further feature of this research project is the integration of microreactor technology as a process concept. By means of this innovative process concept, improvements of both ecological as well as economical criteria are expected. In this project an ecological assessment is also carried out by all project partners.

The four project partners conducting this research project are Bielefeld University, Provadis Hochschule in Frankfurt, the company Invenios Europe GmbH, Mainz, as a „small and medium-sized enterprise“ (SME) as well as Sandoz Industrial Products GmbH at Industriepark Höchst as industrial partner.

Project Operation:

Prof. Dr. Harald Gröger
Universität Bielefeld
Organische Chemie I
Universitätsstr. 25
33615 Bielefeld
Telefon 0521/106205
harald.groeger@uni-bielefeld.de

Prof. Dr. Thomas Bayer
Provadis School of International Management
and Technology AG
Fachbereich Chemieingenieurwesen
Industriepark Höchst, Geb. B845
65926 Frankfurt
Telefon 069 305 28145
Thomas.Bayer@provadis-hochschule.de

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